Description

1-Fluoro-3-Iodo-2-Methyl-5-Nitrobenzene is a high-purity, multi-functional halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring fluorine, iodine, and nitro substituents on a methylated benzene ring, makes it a versatile precursor for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical R&D departments for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those requiring halogenated aromatic cores for bioactivity or as a handle for further functionalization via cross-coupling reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where the nitro and halogen groups contribute to biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for advanced organic materials, such as liquid crystals, organic semiconductors, and specialty polymers.
• Cross-Coupling Reactions: The iodine atom is an excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Stille, Sonogashira couplings), enabling the rapid assembly of complex biaryl and conjugated systems.
• Fluorine Chemistry Studies: Used as a model compound in research exploring the effects of fluorine substitution on aromatic system reactivity, lipophilicity, and metabolic stability.
• Dye and Pigment Synthesis: Acts as an intermediate in the production of specialized halogenated dyes and pigments.

Basic Information

Product Name	1-Fluoro-3-Iodo-2-Methyl-5-Nitrobenzene
CAS No.	264617-02-9
Molecular Formula	C7H5FINO2
Molecular Weight	281.02 g/mol
Synonyms	2-Fluoro-6-iodo-3-nitrotoluene; 3-Iodo-2-methyl-5-nitrofluorobenzene; 2-Methyl-3-iodo-5-nitrofluorobenzene; 1-Fluoro-3-iodo-2-methyl-5-nitrobenzene; Benzene, 1-fluoro-3-iodo-2-methyl-5-nitro-; 5-Nitro-3-iodo-2-fluorotoluene
EINECS	Contact for details

Quality Control

Our 1-Fluoro-3-Iodo-2-Methyl-5-Nitrobenzene is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling and transfer should be minimized under direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.