Description

Methyl 2-(2-Nitrilo-3-Fluorophenylthio)Acetate is a specialized fluorinated aromatic building block designed for advanced organic synthesis. This compound matters for its unique molecular architecture, which combines a nitrile group, a fluorine atom, and a thioether-linked ester moiety, enabling precise modifications in target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used to develop novel herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science: Serves as a monomer or functionalization agent for creating specialty polymers with specific electronic or surface properties.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: A valuable substrate for investigating new fluorination reactions and studying structure-activity relationships (SAR).

Basic Information

Product Name	Methyl 2-(2-Nitrilo-3-Fluorophenylthio)Acetate
CAS No.	262433-37-4
Molecular Formula	C10H8FNO2S
Molecular Weight	225.24 g/mol
Synonyms	Methyl (2-cyano-3-fluorophenylthio)acetate; 2-(2-Cyano-3-fluorophenylthio)acetic acid methyl ester; Acetic acid, 2-[(2-cyano-3-fluorophenyl)thio]-, methyl ester; Methyl 2-[(2-cyano-3-fluorophenyl)sulfanyl]acetate; 3-Fluoro-2-mercaptobenzonitrile acetate methyl ester derivative
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(2-Nitrilo-3-Fluorophenylthio)Acetate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container must be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.