Description

3-Fluoro-2-(Trifluoromethyl)Benzonitrile is a high-value fluorinated aromatic nitrile building block, essential for advanced chemical synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group, makes it a critical intermediate for introducing lipophilicity and metabolic stability into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Functional Material Development: Employed in creating specialty polymers, coatings, and advanced resins with specific chemical resistance and stability properties.
• Chemical Research & Development: A versatile building block for medicinal chemistry, facilitating structure-activity relationship (SAR) studies and library synthesis in drug discovery.

Basic Information

Product Name	3-Fluoro-2-(Trifluoromethyl)Benzonitrile
CAS No.	261951-81-9
Molecular Formula	C8H3F4N
Molecular Weight	189.11 g/mol
Synonyms	2-Cyano-6-fluorobenzotrifluoride; 2-(Trifluoromethyl)-3-fluorobenzonitrile; 3-Fluoro-2-(trifluoromethyl)benzonitrile; 2-Trifluoromethyl-3-fluorobenzonitrile; Benzonitrile, 3-fluoro-2-(trifluoromethyl)-; 3-Fluoro-alpha,alpha,α-trifluoro-o-tolunitrile
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-(Trifluoromethyl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.