Description

3-Fluoro-4-Methylphenylacetonitrile is a versatile fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a reactive cyano group and a fluorine substituent on a methylated benzene ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the development of fluorinated components for liquid crystal displays (LCDs).
• Organic Electronic Materials: Employed in the synthesis of novel organic semiconductors and charge-transport materials for electronic devices.
• Complex Ligand Preparation: Useful for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• General Organic Synthesis: A versatile reagent for introducing the 3-fluoro-4-methylbenzyl moiety into more complex molecular architectures via further functionalization of the nitrile group.

Basic Information

Product Name	3-Fluoro-4-Methylphenylacetonitrile
CAS No.	261951-73-9
Molecular Formula	C9H8FN
Molecular Weight	149.17 g/mol
Synonyms	(3-Fluoro-4-methylphenyl)acetonitrile; 2-(3-Fluoro-4-methylphenyl)acetonitrile; 3-Fluoro-4-methylbenzyl cyanide; 4-Methyl-3-fluorobenzyl cyanide; 3-Fluoro-p-tolylacetonitrile; α-Cyano-3-fluoro-4-methyltoluene; 261951-73-9
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Methylphenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.