Description

2,6-Difluoro-3-Methylphenylacetonitrile is a versatile and high-purity fluorinated aromatic nitrile building block. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its difluoro-methylphenyl core imparts unique biological activity and metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the fluorine atoms for enhanced efficacy and environmental profile.
• Ligand and Catalyst Preparation: Serves as a precursor for specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the creation of fluorinated liquid crystals, polymers, and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2,6-Difluoro-3-Methylphenylacetonitrile
CAS No.	261944-04-1
Molecular Formula	C9H7F2N
Molecular Weight	167.16 g/mol
Synonyms	2,6-Difluoro-3-methylbenzyl cyanide; (2,6-Difluoro-3-methylphenyl)acetonitrile; 2-(2,6-Difluoro-3-methylphenyl)acetonitrile; α-Cyano-2,6-difluoro-3-methyltoluene; Benzeneacetonitrile, 2,6-difluoro-3-methyl-; 261944-04-1; 2,6-Difluoro-3-Methyl Phenyl Acetonitrile
EINECS	Contact for details

Quality Control

Every batch of our 2,6-Difluoro-3-Methylphenylacetonitrile is manufactured and tested under a strict quality management system. We ensure high chemical purity and consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.