Description

2-Chloro-6-Fluoro-3-Methylphenylacetonitrile is a versatile and high-purity halogenated aromatic nitrile intermediate. This compound is valued for its role as a critical building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated phenyl ring for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of advanced polymers and liquid crystals where specific halogen and nitrile functionalities are required.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Chloro-6-Fluoro-3-Methylphenylacetonitrile
CAS No.	261762-94-1
Molecular Formula	C9H7ClFN
Molecular Weight	183.61 g/mol
Synonyms	(2-Chloro-6-fluoro-3-methylphenyl)acetonitrile; 2-Chloro-6-fluoro-3-methylbenzyl cyanide; α-Chloro-2-fluoro-6-methylbenzyl cyanide; 2-Chloro-6-fluoro-m-tolylacetonitrile; 261762-94-1; Benzeneacetonitrile, 2-chloro-6-fluoro-3-methyl-
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Fluoro-3-Methylphenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring traceability and consistency for demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 15°C and 25°C. Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.