Description

2,3-Difluoro-4-Methoxybenzonitrile is a versatile fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both fluorine and methoxy substituents adjacent to a nitrile group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluoromethoxybenzene or benzonitrile core structure.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronics: Employed in the research and development of organic semiconductors and electro-optical materials due to its electron-withdrawing nitrile group and fluorine substituents.
• Advanced Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers with enhanced chemical resistance and specific optical properties.
• Chemical Research & Development: A valuable reagent for method development and exploring new reaction pathways in fluoroorganic chemistry.

Basic Information

Product Name	2,3-Difluoro-4-Methoxybenzonitrile
CAS No.	256417-12-6
Molecular Formula	C9H5F2NO
Molecular Weight	181.14 g/mol
Synonyms	4-Methoxy-2,3-difluorobenzonitrile; 2,3-Difluoro-4-methoxybenzonitrile; 2,3-Difluoro-p-anisonitrile; Benzonitrile, 2,3-difluoro-4-methoxy-; 256417-12-6; 2,3-Difluoro-4-methoxy-benzonitrile
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Methoxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent quality suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.