Description

Banoxantrone (Dihydrochloride) CAS NO 252979-56-9 is a high-purity, synthetic chemical compound of significant interest in advanced pharmaceutical research and development. Its primary value lies in its role as a key intermediate or active pharmaceutical ingredient (API) for investigating novel therapeutic agents. This product is essential for research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in the synthesis and study of complex organic molecules for potential drug candidates.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or reference standard in the synthesis and optimization of new chemical entities (NCEs).
• Preclinical Studies: Used in laboratory-scale experiments to evaluate biological activity, pharmacokinetics, and toxicity profiles.
• Process Chemistry: Employed in route scouting and scale-up studies for the development of efficient and scalable synthetic pathways.
• Analytical Method Development: Acts as a high-purity standard for calibrating analytical instruments like HPLC and LC-MS to ensure accurate quantification.
• Academic Research: Utilized in university and institutional labs for chemical biology studies and structure-activity relationship (SAR) investigations.
• Contract Manufacturing: Supplied to CDMOs for the cGMP or non-GMP production of batches for clinical trial materials (CTM).

Basic Information

Product Name	Banoxantrone (Dihydrochloride)
CAS No.	252979-56-9
Molecular Formula	C23H28N4O6 • 2HCl
Molecular Weight	529.41 g/mol (Free base: 456.50 g/mol)
Synonyms	Banoxantrone Dihydrochloride; AQ4N Dihydrochloride; 1,4-Bis-[[2-(dimethylamino-N-oxide)ethyl]amino]-5,8-dihydroxyanthracene-9,10-dione Dihydrochloride; NSC 709257 Dihydrochloride; Banoxantrone HCl; AQ4N HCl; 3,6-Bis((2-(dimethylamino)ethyl)amino)-2,5-dihydroxy-1,4-benzoquinone Dihydrochloride (tautomeric form)
EINECS	Contact for details

Quality Control

Our Banoxantrone (Dihydrochloride) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis to ensure it meets stringent specifications for research use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Orange to red solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Assay (Titration)	97.0% - 103.0% (on anhydrous basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.