Description

Benzeneacetonitrile, α-Amino-2-Fluoro- (9Ci) is a specialized fluorinated amino nitrile building block. This compound is valued for its unique molecular structure, which incorporates both an amino group and a fluorine atom on the alpha carbon of a phenylacetonitrile scaffold, making it a versatile intermediate for advanced synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of novel herbicides, pesticides, and plant growth regulators that benefit from the stability and bioactivity imparted by the fluorine atom.
• Peptidomimetics & Bioactive Molecule Synthesis: Serves as a constrained amino acid analog for creating peptide-like structures with enhanced metabolic stability.
• Ligand & Catalyst Development: Employed in the preparation of specialized chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Investigated as a monomer or building block for advanced polymers and functional materials with specific electronic or surface properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	Benzeneacetonitrile, α-Amino-2-Fluoro- (9Ci)
CAS No.	252637-90-4
Molecular Formula	C9H9FN2
Molecular Weight	164.18 g/mol
Synonyms	2-Amino-2-fluorophenylacetonitrile; α-Amino-2-fluorobenzeneacetonitrile; (2-Fluorophenyl)(amino)acetonitrile; 2-Fluoro-α-aminobenzeneacetonitrile; 2-Fluoro-2-phenylglycinonitrile; 2-Fluoromandelonitrile, 2-Amino-; (Amino)(2-fluorophenyl)acetonitrile
EINECS	Contact for details

Quality Control

Our Benzeneacetonitrile, α-Amino-2-Fluoro- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (by HPLC), chiral purity (if applicable), and impurity profiles is provided with every shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Chiral Purity (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.