Description

2-[3,5-Bis(Trifluoromethyl)Phenyl]-N'-Hydroxyethanimidamide is a high-value, specialized organic intermediate featuring a bis(trifluoromethyl)phenyl group, a motif known for imparting unique electronic and lipophilic properties. This compound is critical for the synthesis of advanced molecules in pharmaceutical and agrochemical research, where its structure serves as a key building block for creating potent active ingredients. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Serves as a monomer or additive in the development of specialty polymers and coatings with advanced chemical resistance.
• Chemical Synthesis: Employed in organic synthesis for constructing complex molecules via reactions involving its amidoxime functional group.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions.

Basic Information

Product Name	2-[3,5-Bis(Trifluoromethyl)Phenyl]-N'-Hydroxyethanimidamide
CAS No.	244022-74-0
Molecular Formula	C11H8F6N2O
Molecular Weight	298.19 g/mol
Synonyms	2-[3,5-Bis(trifluoromethyl)phenyl]-N'-hydroxyethanimidamide; 2-[3,5-Bis(trifluoromethyl)phenyl]acetamidoxime; 2-(3,5-Bis(trifluoromethyl)phenyl)acetamidoxime; 2-(3,5-Bis(trifluoromethyl)phenyl)-N-hydroxyacetimidamide; 2-(3,5-Bis(trifluoromethyl)phenyl)acetimidamide, N-hydroxy-; (Z)-2-[3,5-Bis(trifluoromethyl)phenyl]-N'-hydroxyethanimidamide
EINECS	Contact for details

Quality Control

Our 2-[3,5-Bis(Trifluoromethyl)Phenyl]-N'-Hydroxyethanimidamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.