Description

4-Fluoro-3-Methoxybenzonitrile is a versatile fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both electron-withdrawing and electron-donating substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, CNS-active compounds, and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating fluorinated aromatic cores used in electronic display materials and organic light-emitting diodes (OLEDs).
• Functional Material Development: Employed in the synthesis of specialty polymers, dyes, and advanced materials requiring specific electronic or photophysical properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex aryl groups into molecular frameworks.

Basic Information

Item	Details
Product Name	4-Fluoro-3-Methoxybenzonitrile
CAS No.	243128-37-2
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	3-Methoxy-4-fluorobenzonitrile; 4-Fluoro-3-methoxybenzonitrile; 4-Fluoro-m-anisonitrile; 3-Cyano-4-fluoroanisole; 4-Fluoro-3-methoxy-phenyl cyanide; 4-Fluoro-3-methoxybenzenecarbonitrile; 1-Cyano-2-fluoro-5-methoxybenzene; FMOBN
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Methoxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.