Description

2,3,5-Trifluorobenzonitrile is a high-purity fluorinated aromatic nitrile building block essential for advanced organic synthesis. This compound is valued for its trifluoromethyl-substituted benzene ring, which imparts unique electronic and steric properties critical for modulating the bioactivity and physicochemical characteristics of target molecules. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used in the research and production of modern pesticides and herbicides, where the fluorine atoms enhance metabolic stability and lipophilicity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Functional Polymer Monomer: Incorporated into specialty polymers to improve chemical resistance, thermal stability, and optical properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex biaryl structures.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new fluorination chemistry and building molecular libraries.

Basic Information

Product Name	2,3,5-Trifluorobenzonitrile
CAS No.	241154-09-6
Molecular Formula	C7H2F3N
Molecular Weight	157.09 g/mol
Synonyms	2,3,5-Trifluorobenzene carbonitrile; 2,3,5-Trifluorophenyl cyanide; Benzonitrile, 2,3,5-trifluoro-; 2,3,5-Trifluorobenzonitrile; 241154-09-6; 2,3,5-Trifluorobenzyl nitrile (common name); TFB (abbreviation)
EINECS	Contact for details

Quality Control

Our 2,3,5-Trifluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.