Description

3-Fluoro-5-(Trifluoromethyl)Phenylacetonitrile is a versatile and high-value fluorinated aromatic nitrile building block. This compound is critical for introducing the unique physicochemical properties of fluorine into advanced molecular architectures, enhancing lipophilicity, metabolic stability, and binding affinity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl and fluorine groups confer improved biological activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display and lighting technologies, improving performance and stability.
• Functional Material Research: Employed in organic synthesis for creating novel polymers, ligands for catalysis, and specialty chemicals with tailored properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and custom chemical synthesis projects.

Basic Information

Product Name	3-Fluoro-5-(Trifluoromethyl)Phenylacetonitrile
CAS No.	239087-12-8
Molecular Formula	C9H5F4N
Molecular Weight	203.14 g/mol
Synonyms	2-[3-Fluoro-5-(trifluoromethyl)phenyl]acetonitrile; (3-Fluoro-5-trifluoromethylphenyl)acetonitrile; 3-Fluoro-α-(trifluoromethyl)benzeneacetonitrile; 3-Fluoro-5-(trifluoromethyl)benzyl cyanide; 2-(3-Fluoro-5-(trifluoromethyl)phenyl)ethanenitrile; 239087-12-8; 3-Fluoro-5-trifluoromethylphenylacetonitrile
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Trifluoromethyl)Phenylacetonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical 98.0-99.5%)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.