Description

2-Fluoro-3-(trifluoromethyl)phenylacetonitrile is a versatile fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its value lies in the unique reactivity imparted by the combination of the electron-withdrawing nitrile group and the fluorine/trifluoromethyl substituents on the phenyl ring. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Material (LC) Development: Serves as a building block for fluorinated liquid crystal compounds used in advanced display technologies.
• Organic Light-Emitting Diode (OLED) Materials: Employed in the synthesis of electron-transport or host materials for OLED devices due to its electronic properties.
• Advanced Polymer Chemistry: Acts as a monomer or modifier for creating high-performance, fluorinated polymers with specialized chemical resistance and thermal stability.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) for constructing biaryl systems.

Basic Information

Product Name	2-Fluoro-3-(Trifluoromethyl)Phenylacetonitrile
CAS No.	239087-10-6
Molecular Formula	C9H5F4N
Molecular Weight	203.14 g/mol
Synonyms	2-Fluoro-3-(trifluoromethyl)benzyl cyanide; (2-Fluoro-3-(trifluoromethyl)phenyl)acetonitrile; α-Cyano-2-fluoro-3-(trifluoromethyl)toluene; 2-Fluoro-α-(trifluoromethyl)phenylacetonitrile; 3-Trifluoromethyl-2-fluorophenylacetonitrile; [2-Fluoro-3-(trifluoromethyl)phenyl]acetonitrile; 239087-10-6; 2-Fluoro-3-trifluoromethylphenylacetonitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-(trifluoromethyl)phenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.