Description

Daunorubicin 4’-o-α-D-Glucoside Sodium Salt is a semi-synthetic glycosylated derivative of the potent anthracycline antibiotic, daunorubicin. This chemical modification is designed to alter the pharmacokinetic profile and potentially modulate the biological activity of the parent compound, making it a valuable intermediate for advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel chemotherapeutic agents and the study of drug metabolism and targeting.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel daunorubicin analogs and prodrugs for oncology research.
• Biochemical Research: Used as a substrate or reference standard in studies investigating glycosyltransferase enzymes and anthracycline metabolism.
• Anticancer Agent Development: Employed in structure-activity relationship (SAR) studies to develop new chemotherapeutic compounds with improved efficacy or reduced side effects.
• Prodrug Synthesis: Acts as a precursor for creating targeted prodrugs designed for specific enzyme-activated release in tumor cells.
• Reference Standard: Utilized in analytical laboratories for method development and quality control (HPLC, LC-MS) of related anthracycline compounds.

Basic Information

Product Name	Daunorubicin 4’-o-α-D-Glucoside Sodium Salt
CAS No.	229314-76-5
Molecular Formula	C35H41NO17 • Na
Molecular Weight	Contact for details
Synonyms	4'-O-α-D-Glucopyranosyldaunorubicin Sodium Salt; Daunorubicin 4'-α-D-glucoside Sodium Salt; Daunorubicin 4'-O-α-D-glucoside Sodium Salt; 4'-O-(α-D-Glucopyranosyl)daunorubicin Sodium Salt; Daunorubicin 4'-O-α-glucoside Sodium Salt
EINECS	Contact for details

Quality Control

Our Daunorubicin 4’-o-α-D-Glucoside Sodium Salt is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or desiccated conditions after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	Red to orange-red powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.