Description

Benzonitrile, 2-Fluoro-5-(Hydroxymethyl)- (9Ci) CAS NO 227609-85-0 is a high-purity fluorinated benzonitrile derivative, distinguished by its hydroxymethyl functional group. This compound serves as a versatile and critical building block in advanced organic synthesis, enabling the introduction of both fluorine and alcohol moieties into complex molecular architectures. It is primarily utilized by pharmaceutical and agrochemical research & development teams for the synthesis of novel active ingredients, including potential drug candidates and specialty crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with tailored thermal and chemical resistance properties.
• Organic Electronics: Employed in the synthesis of electron-transport materials and small-molecule semiconductors for OLEDs and organic photovoltaics.
• Chemical Research: A valuable reagent for method development and exploring new fluorination and functionalization reactions in academic and industrial laboratories.

Basic Information

Product Name	Benzonitrile, 2-Fluoro-5-(Hydroxymethyl)- (9Ci)
CAS No.	227609-85-0
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	2-Fluoro-5-(hydroxymethyl)benzonitrile; 5-(Hydroxymethyl)-2-fluorobenzonitrile; (2-Fluoro-5-cyanophenyl)methanol; 2-Fluoro-5-cyanobenzyl alcohol; 2-Fluoro-5-(hydroxymethyl)phenyl cyanide; 2-Fluoro-5-cyanobenzyl alcohol; 5-Cyano-2-fluorobenzyl alcohol
EINECS	Contact for details

Quality Control

Our Benzonitrile, 2-Fluoro-5-(Hydroxymethyl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, NMR, and FTIR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a light-proof secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.