Description

4,5-Diamino-2-Fluorobenzonitrile is a high-purity, multi-functional aromatic building block featuring both amino and nitrile groups on a fluorinated benzene ring. This compound is critical for synthesizing complex heterocyclic structures and advanced pharmaceutical intermediates where precise molecular architecture is required. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides requiring specific fluorinated scaffolds.
• Dye and Pigment Manufacturing: Serves as a building block for creating specialized fluorinated dyes and colorants with enhanced properties.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other advanced polymeric materials.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed reactions like Buchwald-Hartwig amination for creating complex amines.
• Chemical Research & Development: A valuable reagent for exploring new synthetic pathways and creating custom chemical libraries.

Basic Information

Product Name	4,5-Diamino-2-Fluorobenzonitrile
CAS No.	226701-59-3
Molecular Formula	C7H6FN3
Molecular Weight	151.14 g/mol
Synonyms	2-Fluoro-4,5-diaminobenzonitrile; 4,5-Diamino-2-fluorobenzene-1-carbonitrile; 2-Fluoro-1,2-diaminobenzonitrile; 1-Cyano-2-fluoro-4,5-diaminobenzene; Benzonitrile, 4,5-diamino-2-fluoro-; 226701-59-3; 4,5-Diamino-2-fluorobenzonitrile
EINECS	Contact for details

Quality Control

Our 4,5-Diamino-2-Fluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store under an inert atmosphere such as nitrogen or argon for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.