Description

Efletirizine 2Hcl CAS NO 225367-66-8 is the dihydrochloride salt form of Efletirizine, a high-purity active pharmaceutical ingredient (API) and key chemical intermediate. This compound is critical for ensuring the efficacy and consistency of final pharmaceutical formulations. It is primarily required by manufacturers in the pharmaceutical and biotechnology sectors engaged in the research, development, and production of advanced therapeutic agents.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active component in finished dosage forms.
• Reference Standard: Serves as a certified standard for quality control and analytical method development in laboratories.
• Biochemical Research: Used as a key reagent in pharmacological and pharmacokinetic studies.
• Process Development: Employed as a critical intermediate in the scale-up and optimization of synthetic routes.
• Formulation Development: Essential for creating stable and bioavailable drug formulations in pre-clinical and clinical stages.

Basic Information

Product Name	Efletirizine 2Hcl
CAS No.	225367-66-8
Molecular Formula	C21H27Cl2N3O3
Molecular Weight	464.37 g/mol
Synonyms	Efletirizine Dihydrochloride; 2-[2-[4-[(R)-(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride; (R)-2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetic acid dihydrochloride; E-0659; Levocetirizine Impurity; Cetirizine Related Compound
EINECS	Contact for details

Quality Control

Our Efletirizine 2Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.