Description

Benzene, 2-(Chloromethyl)-1-Fluoro-3-Nitro- is a versatile and highly functionalized aromatic building block. Its unique combination of reactive halogen and nitro substituents makes it a critical intermediate for constructing complex molecular architectures in advanced synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and nitro-substituted aromatic rings.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in organic and organometallic chemistry to synthesize novel ligands and catalytic complexes.
• Dye and Pigment Intermediate: Provides a foundational structure for synthesizing complex colorants and functional dyes.
• Cross-Coupling Reactions: A valuable substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings due to its halogen functionality.

Basic Information

Product Name	Benzene, 2-(Chloromethyl)-1-Fluoro-3-Nitro-
CAS No.	225112-38-9
Molecular Formula	C7H5ClFNO2
Molecular Weight	189.57 g/mol
Synonyms	2-(Chloromethyl)-1-Fluoro-3-Nitrobenzene; 1-Fluoro-2-(chloromethyl)-3-nitrobenzene; 3-Nitro-2-(chloromethyl)fluorobenzene; (2-Chloromethyl)-1-fluoro-3-nitrobenzene; 2-Chloromethyl-1-fluoro-3-nitrobenzene; Benzene, 1-fluoro-2-(chloromethyl)-3-nitro-; α-Chloro-2-fluoro-6-nitrobenzyl alcohol (tautomer); 2-Fluoro-6-nitrobenzyl chloride
EINECS	Contact for details

Quality Control

Our Benzene, 2-(Chloromethyl)-1-Fluoro-3-Nitro- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, minimize exposure during handling and transfer.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.