Description

1-Nitro-2,4-Bis-(Trifluoromethyl)Benzene is a high-value fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both nitro and trifluoromethyl groups, makes it a critical building block for creating complex molecules with tailored electronic and physical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Dye & Pigment Manufacturing: Employed in the production of specialized, high-performance dyes and pigments requiring nitro and fluorine substituents.
• Organic Synthesis Reagent: Acts as a versatile reagent in cross-coupling reactions and nucleophilic aromatic substitution for introducing fluorinated aromatic systems.
• Polymer Modification: Used to incorporate fluorinated aromatic units into polymer backbones to alter thermal stability, chemical resistance, and optical properties.

Basic Information

Product Name	1-Nitro-2,4-Bis-(Trifluoromethyl)Benzene
CAS No.	224044-97-7
Molecular Formula	C8H3F6NO2
Molecular Weight	259.11 g/mol
Synonyms	2,4-Bis(trifluoromethyl)-1-nitrobenzene; 2,4-Bis(trifluoromethyl)nitrobenzene; 1-Nitro-2,4-di(trifluoromethyl)benzene; Benzene, 1-nitro-2,4-bis(trifluoromethyl)-; α,α,α,α',α',α'-Hexafluoro-2,4-dimethyl-1-nitrobenzene
EINECS	Contact for details

Quality Control

Our 1-Nitro-2,4-Bis-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.