Description

Benzonitrile, 2,3-Difluoro-6-Hydroxy- (9Ci) is a high-purity fluorinated aromatic nitrile derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring both a nitrile group and hydroxyl and fluorine substituents, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require precise, high-quality intermediates for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays (LCDs).
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers, including polyamides and polyesters, to impart specific chemical resistance or thermal properties.
• Organic Synthesis & Research: A valuable reagent in academic and industrial R&D for constructing complex heterocycles and fluorinated aromatic systems via reactions like nucleophilic aromatic substitution.
• Material Science: Employed in the development of organic semiconductors and electronic materials due to its electron-withdrawing nitrile group and potential for fine-tuning electronic properties.

Basic Information

Product Name	Benzonitrile, 2,3-Difluoro-6-Hydroxy- (9Ci)
CAS No.	221202-36-4
Molecular Formula	C7H3F2NO
Molecular Weight	155.10 g/mol
Synonyms	2,3-Difluoro-6-hydroxybenzonitrile; 6-Cyano-2,3-difluorophenol; 2,3-Difluoro-6-hydroxybenzenecarbonitrile; 2,3-Difluoro-6-phenol carbonitrile; Phenol, 2,3-difluoro-6-cyano-; 2,3-Difluoro-6-cyanophenol; 6-Hydroxy-2,3-difluorobenzonitrile
EINECS	Contact for details

Quality Control

Every batch of Benzonitrile, 2,3-Difluoro-6-Hydroxy- (9Ci) is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency meet the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.