Description

2,4,5-Trifluorophenylacetonitrile is a high-value fluorinated aromatic nitrile building block. This compound is essential for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical industries, due to the unique electronic and steric properties imparted by its trifluoromethylphenyl moiety. It serves as a critical intermediate for researchers and manufacturers developing active pharmaceutical ingredients (APIs), advanced materials, and specialty chemicals. The product is supplied to meet the stringent quality requirements of global R&D and production facilities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays.
• Organic Electronics: Employed in the synthesis of novel organic semiconductors and charge-transport materials.
• Chemical Research & Development: A versatile reagent for academic and industrial research in medicinal chemistry and material science.
• Fluorine Chemistry: Used as a standard or starting material for further functionalization in specialty fluorine chemistry.

Basic Information

Product Name	2,4,5-Trifluorophenylacetonitrile
CAS No.	220141-74-2
Molecular Formula	C8H4F3N
Molecular Weight	171.12 g/mol
Synonyms	(2,4,5-Trifluorophenyl)acetonitrile; 2-(2,4,5-Trifluorophenyl)acetonitrile; 2,4,5-Trifluorobenzeneacetonitrile; α-Cyano-2,4,5-trifluorotoluene; 2,4,5-Trifluorophenyl Cyanomethyl; 2,4,5-Trifluoro-benzeneacetonitrile; 2,4,5-Trifluorobenzyl cyanide
EINECS	Contact for details

Quality Control

Our 2,4,5-Trifluorophenylacetonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.