Description

Benzonitrile, 2-Amino-4,5-Difluoro- (9Ci) CAS NO 219823-49-1 is a high-purity, fluorinated aromatic nitrile derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which introduces both amino and fluorine functionalities onto the benzonitrile core, enabling precise modifications in target molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoro-amino substitution pattern can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and organic electronic materials to modify electronic properties and stability.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes for bioimaging and diagnostic applications.

Basic Information

Product Name	Benzonitrile, 2-Amino-4,5-Difluoro- (9Ci)
CAS No.	219823-49-1
Molecular Formula	C7H4F2N2
Molecular Weight	154.12 g/mol
Synonyms	2-Amino-4,5-difluorobenzonitrile; 4,5-Difluoro-2-aminobenzonitrile; 2-Cyano-4,5-difluoroaniline; 3,4-Difluoro-6-aminobenzonitrile; 2-Amino-4,5-difluorophenyl cyanide; Benzonitrile, 2-amino-4,5-difluoro-; 219823-49-1
EINECS	Contact for details

Quality Control

Our Benzonitrile, 2-Amino-4,5-Difluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.