Description

4-Bromo-2-Chloro-6-Fluorobenzonitrile is a high-purity halogenated benzonitrile derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides multiple reactive sites for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, especially in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging its halogenated aromatic core.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers and liquid crystals.
• Chemical Research & Development: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution in academic and industrial R&D labs.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of complex colorants and functional dyes.

Basic Information

Product Name	4-Bromo-2-Chloro-6-Fluorobenzonitrile
CAS No.	218797-72-9
Molecular Formula	C7H2BrClFN
Molecular Weight	234.45 g/mol
Synonyms	2-Chloro-4-bromo-6-fluorobenzonitrile; 6-Fluoro-2-chloro-4-bromobenzonitrile; 4-Bromo-2-chloro-6-fluorophenyl cyanide; Benzonitrile, 4-bromo-2-chloro-6-fluoro-; 218797-72-9; BCFBN; 2-Chloro-4-bromo-6-fluorobenzene carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-6-Fluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures batch-to-batch consistency, meeting the stringent requirements of GMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure the container is kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.