Description

3-Bromo-2-Fluoro-6-Iodobenzonitrile is a high-value, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working on new active ingredients, where its distinct reactivity profile enables precise structural modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a building block for creating specialized organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Sonogashira cross-coupling reactions due to the presence of bromo and iodo substituents.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	3-Bromo-2-Fluoro-6-Iodobenzonitrile
CAS No.	217816-66-5
Molecular Formula	C7H2BrFIN
Molecular Weight	325.91 g/mol
Synonyms	2-Fluoro-3-bromo-6-iodobenzonitrile; 6-Iodo-3-bromo-2-fluorobenzonitrile; Benzonitrile, 3-bromo-2-fluoro-6-iodo-; 3-Bromo-2-fluoro-6-iodobenzene carbonitrile; 217816-66-5; 2-Fluoro-3-bromo-6-iodo-benzonitrile; 3-Br-2-F-6-I-benzonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Fluoro-6-Iodobenzonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to support our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.