Description

3-Fluoro-5-Methylbenzonitrile is a versatile fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a nitrile group and a fluorine atom on a methyl-substituted benzene ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing the fluoromethylphenyl moiety into bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display applications.
• Organic Light-Emitting Diodes (OLEDs): Employed in the development of electron-transport or host materials for high-efficiency display and lighting technologies.
• Advanced Polymer Chemistry: Acts as a monomer or modifier for creating specialty polymers with unique thermal, chemical, or surface properties.
• Chemical Research & Development: A valuable reagent for methodological studies in cross-coupling reactions, cyanation chemistry, and fluorination techniques.

Basic Information

Product Name	3-Fluoro-5-Methylbenzonitrile
CAS No.	216976-30-6
Molecular Formula	C8H6FN
Molecular Weight	135.14 g/mol
Synonyms	5-Methyl-3-fluorobenzonitrile; 3-Fluoro-5-methylbenzenecarbonitrile; Benzonitrile, 3-fluoro-5-methyl-; 3-Fluoro-5-tolunitrile; 3-Fluoro-5-methylphenyl cyanide; 216976-30-6; 3-Fluoro-5-methyl-benzonitrile
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Methylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.