Description

2,2,3,3-Tetrafluoropropanal Hydrate is a specialized fluorinated aldehyde derivative, a key building block in advanced organic synthesis. Its value lies in introducing the tetrafluoroethane moiety, which can impart significant changes to the lipophilicity, metabolic stability, and electronic properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, as well as in materials science for creating fluorinated polymers and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), where fluorine atoms enhance bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, pesticides, and fungicides, leveraging fluorine's ability to improve efficacy and environmental profile.
• Fluorinated Polymer Research: Acts as a monomer or modifying agent in the production of specialty polymers with enhanced chemical resistance, thermal stability, and unique surface properties.
• Liquid Crystal & Electronic Materials: Employed in the synthesis of fluorinated components for liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs) due to its influence on dielectric constant and molecular alignment.
• Organic Synthesis Building Block: Provides a versatile handle for introducing the -CF2CF2CHO unit into more complex molecular architectures via standard carbonyl chemistry.

Basic Information

Product Name	2,2,3,3-Tetrafluoropropanal Hydrate
CAS No.	215858-32-5
Molecular Formula	C3H4F4O2
Molecular Weight	148.06 g/mol
Synonyms	2,2,3,3-Tetrafluoro-1-propanal Hydrate; Tetrafluoropropanal Hydrate; 2,2,3,3-Tetrafluoropropanal Monohydrate; 1,1,2,2-Tetrafluoro-3-oxopropane Hydrate; Propanal, 2,2,3,3-tetrafluoro-, hydrate (1:1); NSC 339063; 3,3,4,4-Tetrafluorobutanal Hydrate (alternative numbering)
EINECS	Contact for details

Quality Control

Our 2,2,3,3-Tetrafluoropropanal Hydrate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (by NMR or GC), water content (Karl Fischer), and impurity profile. Our quality system supports compliance with cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider under an inert atmosphere (e.g., nitrogen or argon). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC or NMR)	≥ 95.0%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.