Description

8-Fluoroquinoline-4-Carboxylic Acid is a high-purity fluorinated quinoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to introduce fluorine atoms for enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated quinolone antibiotics and other bioactive molecules.
• Agrochemical Research: Used in developing new generation herbicides and pesticides with improved efficacy.
• Material Science: Serves as a precursor for functionalized ligands and fluorophores in advanced materials.
• Chemical Synthesis: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Academic & Contract Research: Utilized in university and CRO laboratories for exploratory research and custom synthesis projects.

Basic Information

Product Name	8-Fluoroquinoline-4-Carboxylic Acid
CAS No.	215801-73-3
Molecular Formula	C10H6FNO2
Molecular Weight	191.16 g/mol
Synonyms	8-Fluoro-4-quinolinecarboxylic acid; 8-Fluoroquinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 8-fluoro-; 8-Fluoro-4-quinolincarboxylic acid; 8-Fluoro-quinoline-4-carboxylic acid; 215801-73-3; 8-Fluoro-4-carboxyquinoline
EINECS	Contact for details

Quality Control

Our 8-Fluoroquinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.