Description

Bamirastine CAS NO 215529-47-8 is a selective histamine H1 receptor antagonist belonging to the piperidine chemical class. This compound is of significant commercial interest for its potential in developing novel therapeutic agents targeting allergic conditions. It is primarily utilized by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of advanced intermediates and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the research and development of new antihistamine drugs.
• Allergy Research: Used in preclinical studies to investigate mechanisms of histamine H1 receptor antagonism.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Chemical Synthesis: Employed in organic synthesis for creating novel chemical entities with potential biological activity.
• Academic Research: Utilized in university and institutional labs for pharmacological and medicinal chemistry studies.

Basic Information

Product Name	Bamirastine
CAS No.	215529-47-8
Molecular Formula	C21H24FN3O2
Molecular Weight	369.44 g/mol
Synonyms	Bamirastine; 1-[2-[4-(Diphenylmethoxy)piperidino]ethyl]-2-(4-fluorophenyl)-1,2-dihydro-4(3H)-quinazolinone; UNII-3Q5QTG78N8; 3Q5QTG78N8; BRN 0972840; CHEMBL2103879; DTXSID6047660
EINECS	Contact for details

Quality Control

Our Bamirastine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is moisture-sensitive (hygroscopic) and should be handled under inert conditions when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.