Description

3-(Trifluoromethyl)-4-Formylbenzonitrile is a high-purity, multi-functional aromatic building block featuring both a formyl and a nitrile group on a trifluoromethyl-substituted benzene ring. This compound is valued for its unique reactivity profile, enabling its use as a versatile intermediate in the synthesis of complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers due to its electron-withdrawing substituents.
• Chemical Biology Probes: Utilized as a scaffold for designing fluorescent tags, enzyme inhibitors, and other molecular probes for biological research.

Basic Information

Product Name	3-(Trifluoromethyl)-4-Formylbenzonitrile
CAS No.	211796-64-4
Molecular Formula	C9H4F3NO
Molecular Weight	199.13 g/mol
Synonyms	4-Cyano-2-(trifluoromethyl)benzaldehyde; 2-(Trifluoromethyl)-4-cyanobenzaldehyde; 4-Formyl-3-(trifluoromethyl)benzonitrile; 4-Cyano-α,α,α-trifluoro-m-tolualdehyde; 3-(Trifluoromethyl)-4-cyanobenzaldehyde; 4-Cyano-2-trifluoromethylbenzaldehyde; 2-Trifluoromethyl-4-cyanobenzaldehyde; 4-Cyano-α,α,α-trifluoro-m-toluic aldehyde
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)-4-Formylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in regulated environments, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.