Description

Sabarubicin CAS NO 211100-13-9 is a synthetic anthracycline derivative and a potent topoisomerase II inhibitor. This compound is of significant interest in pharmaceutical research and development due to its established antitumor activity and potential as a chemotherapeutic agent. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in oncology drug discovery and preclinical studies.

Application

• Oncology Research: A key reference standard and active pharmaceutical ingredient (API) in the investigation of novel cancer therapies.
• Biochemical Studies: Used to study mechanisms of topoisomerase II inhibition and DNA intercalation in cellular models.
• Preclinical Development: Serves as a critical compound for pharmacokinetic, pharmacodynamic, and toxicology profiling in animal studies.
• Pharmaceutical Intermediates: Acts as a high-value intermediate in the synthesis of more complex anthracycline-based drug candidates.
• Academic Research: Employed in university and institutional labs for fundamental cancer biology and medicinal chemistry projects.
• Quality Control: Used as an analytical reference standard for the identification and assay of related pharmaceutical products.

Basic Information

Product Name	Sabarubicin
CAS No.	211100-13-9
Molecular Formula	C30H31NO11
Molecular Weight	581.57 g/mol
Synonyms	MEN 10755; (7S,9S)-9-Acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione; 2''-(R)-O-Methyl-4''-epi-daunorubicin; 4''-Epi-2''-O-methyl-4-demethoxydaunorubicin; Sabarubicin Hydrochloride (salt form)
EINECS	Contact for details

Quality Control

Our Sabarubicin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis to ensure it meets high-purity standards suitable for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants and inert atmosphere conditions.

Specification

Item	Specification
Appearance	Red to orange-red powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.