Description

4-(2-(Trifluoromethyl)Phenyl)-1,2,3,6-Tetrahydropyridine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific trifluoromethylphenyl-substituted tetrahydropyridine structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its unique scaffold.
• API Development: Serves as a precursor in the multi-step synthesis of complex target molecules for preclinical and clinical studies.
• Chemical Biology Probes: Employed in the development of tool compounds for investigating biological pathways and target validation.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing specialized compounds for client projects.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological research.

Basic Information

Product Name	4-(2-(Trifluoromethyl)Phenyl)-1,2,3,6-Tetrahydropyridine Hydrochloride
CAS No.	208989-34-8
Molecular Formula	C12H13ClF3N
Molecular Weight	263.69 g/mol
Synonyms	4-[2-(Trifluoromethyl)phenyl]-1,2,3,6-tetrahydropyridine hydrochloride; 4-(2-Trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine HCl; 1,2,3,6-Tetrahydro-4-[2-(trifluoromethyl)phenyl]pyridine hydrochloride; 4-(α,α,α-Trifluoro-o-tolyl)-1,2,3,6-tetrahydropyridine hydrochloride; 208989-34-8 (CAS); 4-(2-(Trifluoromethyl)phenyl)-3,6-dihydro-2H-pyridine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(2-(Trifluoromethyl)Phenyl)-1,2,3,6-Tetrahydropyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.