Description

5-Bromo-2-Fluoro-4-Nitrotoluene is a high-purity halogenated aromatic compound serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring bromine, fluorine, and nitro substituents on a toluene backbone, makes it an invaluable intermediate for creating complex molecules with tailored properties. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, pesticides, and fungicides, leveraging the bioactivity of its halogen and nitro groups.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex organic dyes and pigments due to its nitro-aromatic structure.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Organic Synthesis Building Block: Provides a versatile platform for nucleophilic substitution and reduction reactions to access a wide array of fluorinated and brominated derivatives.

Basic Information

Product Name	5-Bromo-2-Fluoro-4-Nitrotoluene
CAS No.	208165-95-1
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.02 g/mol
Synonyms	2-Fluoro-5-bromo-4-nitrotoluene; 4-Nitro-5-bromo-2-fluorotoluene; Toluene, 5-bromo-2-fluoro-4-nitro-; 5-Bromo-2-fluoro-1-methyl-4-nitrobenzene; 1-Bromo-4-fluoro-2-methyl-5-nitrobenzene; 2-Fluoro-4-nitro-5-bromotoluene; 5-Bromo-2-fluoro-4-nitro-1-methylbenzene
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoro-4-Nitrotoluene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.