Description

5-Chloro-3-Fluoro-Pyridine-2-Carbonitrile is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters as a versatile precursor for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized pyridines for electronic materials, liquid crystals, and organic semiconductors.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis projects and scale-up services for clients requiring specific fluorinated and chlorinated pyridine derivatives.

Basic Information

Product Name	5-Chloro-3-Fluoro-Pyridine-2-Carbonitrile
CAS No.	207994-11-4
Molecular Formula	C6H2ClFN2
Molecular Weight	156.54 g/mol
Synonyms	2-Cyano-5-chloro-3-fluoropyridine; 3-Fluoro-5-chloropyridine-2-carbonitrile; 5-Chloro-3-fluoropyridine-2-carbonitrile; 5-Chloro-3-fluoro-2-pyridinecarbonitrile; 2-Pyridinecarbonitrile, 5-chloro-3-fluoro-; 5-Chloro-3-fluoropicolinonitrile
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-3-Fluoro-Pyridine-2-Carbonitrile is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, GC, NMR, and mass spectrometry, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.