Description

1,1'-Biphenyl, 4-Fluoro-3-Nitro- is a high-purity, specialized biphenyl derivative distinguished by its strategic fluorine and nitro substituents. This compound serves as a critical advanced intermediate in the synthesis of complex organic molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), liquid crystal materials, and functional dyes who require reliable access to high-quality, structurally precise building blocks.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated nitroaromatic structure.
• Liquid Crystal Materials: Serves as a core component or precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the development of organic semiconductors and charge-transport materials due to its conjugated biphenyl system.
• Dyestuff & Pigment Intermediate: Functions as a precursor for synthesizing specialized azo dyes and high-performance pigments.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create more complex biaryl systems.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new fluorinated aromatic compounds and their reactivity.

Basic Information

Product Name	1,1'-Biphenyl, 4-Fluoro-3-Nitro-
CAS No.	206879-57-4
Molecular Formula	C₁₂H₈FNO₂
Molecular Weight	217.20 g/mol
Synonyms	4-Fluoro-3-nitro-1,1'-biphenyl; 4-Fluoro-3-nitrobiphenyl; 3-Nitro-4-fluorobiphenyl; [1,1'-Biphenyl]-4-fluoro-3-nitro-; 4-Fluoro-3-nitrodiphenyl; 3-Nitro-4-fluorodiphenyl; Biphenyl, 4-fluoro-3-nitro-
EINECS	Contact for details

Quality Control

Our production of 1,1'-Biphenyl, 4-Fluoro-3-Nitro- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the rigorous demands of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.