Description

Cyclopentanecarboxylic Acid, 1-Fluoro-2-Oxo-, Methyl Ester, (-)- (9Ci) is a high-purity, chiral fluorinated building block essential for advanced organic synthesis. This compound matters for its role in introducing both fluorine and a specific stereocenter into complex molecular architectures, enabling the development of novel bioactive compounds. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of advanced, fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Material Science Precursor: Employed in the synthesis of specialized fluorinated polymers or liquid crystals with unique electronic or optical properties.
• Fluorine Chemistry Studies: An important reagent for academic and industrial research exploring new methodologies in organofluorine chemistry.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 1-Fluoro-2-Oxo-, Methyl Ester, (-)- (9Ci)
CAS No.	204457-43-2
Molecular Formula	C7H9FO3
Molecular Weight	160.14 g/mol
Synonyms	(-)-Methyl 1-Fluoro-2-oxocyclopentanecarboxylate; (1R)-1-Fluoro-2-oxocyclopentanecarboxylic Acid Methyl Ester; Methyl (1R)-1-Fluoro-2-oxocyclopentanecarboxylate; 1-Fluoro-2-oxocyclopentanecarboxylic Acid Methyl Ester, (-)-; (R)-Methyl 1-Fluoro-2-oxocyclopentanecarboxylate; 204457-43-2; 1-Fluoro-2-oxocyclopentanecarboxylic acid, methyl ester, (1R)-
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxylic Acid, 1-Fluoro-2-Oxo-, Methyl Ester, (-)- (9Ci) is manufactured under strict quality systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity determination by HPLC and identity confirmation by NMR and IR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.