Description

2,4-Bis(Trifluoromethyl)Phenylacetonitrile is a high-value fluorinated aromatic nitrile building block. This compound is prized for its unique electronic properties imparted by the two trifluoromethyl groups, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the trifluoromethyl groups enhance lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), contributing to improved performance and durability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart chemical resistance, thermal stability, and unique surface properties.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions, cyanoalkylations, and as a ligand precursor in organometallic catalysis.
• Material Science Research: Employed in academic and industrial R&D for creating novel fluorinated compounds with specific electronic or optical characteristics.

Basic Information

Product Name	2,4-Bis(Trifluoromethyl)Phenylacetonitrile
CAS No.	201789-28-8
Molecular Formula	C10H5F6N
Molecular Weight	253.15 g/mol
Synonyms	2,4-Bis(trifluoromethyl)benzyl cyanide; [2,4-Bis(trifluoromethyl)phenyl]acetonitrile; α-(2,4-Bis(trifluoromethyl)phenyl)acetonitrile; 2,4-Bis(trifluoromethyl)benzeneacetonitrile; (2,4-Bis(trifluoromethyl)phenyl)ethanenitrile; 2,4-Di(trifluoromethyl)phenylacetonitrile
EINECS	Contact for details

Quality Control

Our 2,4-Bis(Trifluoromethyl)Phenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.