Description

1-(3-(Trifluoromethyl)Phenyl)Cyclobutanecarbonitrile is a high-value, fluorinated organic building block characterized by its cyclobutane ring and nitrile functionality. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals due to its unique structural motifs. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for specialized ligands in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of monomers and specialty polymers with tailored thermal and chemical resistance properties.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research exploring the effects of fluorine substitution on molecular properties and reactivity.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, multi-step organic transformations.

Basic Information

Product Name	1-(3-(Trifluoromethyl)Phenyl)Cyclobutanecarbonitrile
CAS No.	29786-43-4
Molecular Formula	C12H10F3N
Molecular Weight	225.21 g/mol
Synonyms	3-(3-(Trifluoromethyl)phenyl)cyclobutanecarbonitrile; 1-[3-(Trifluoromethyl)phenyl]cyclobutanecarbonitrile; α-(3-(Trifluoromethyl)phenyl)cyclobutanecetonitrile; m-(Trifluoromethyl)phenylcyclobutanecarbonitrile; Cyclobutanecarbonitrile, 1-[3-(trifluoromethyl)phenyl]-; 3-(α-Cyanocyclobutyl)benzotrifluoride
EINECS	Contact for details

Quality Control

Our 1-(3-(Trifluoromethyl)Phenyl)Cyclobutanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.