Description

1-(2-(Trifluoromethyl)Phenyl)Cyclobutane-1-Carbonitrile is a specialized organic intermediate featuring a cyclobutane ring and a trifluoromethylphenyl group. This compound is valued for its unique structural motif, which imparts desirable properties such as metabolic stability and lipophilicity, making it a critical building block in advanced synthetic chemistry. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for organic electronic materials, contributing to the molecular framework of charge-transport or emissive layers.
• Fluorine Chemistry Research: An important compound for academic and industrial research exploring the effects of fluorine substitution on molecular properties and reactivity.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical manufacturers for the production of bespoke compounds and complex molecules under cGMP or ISO standards.

Basic Information

Product Name	1-(2-(Trifluoromethyl)Phenyl)Cyclobutane-1-Carbonitrile
CAS No.	29786-42-3
Molecular Formula	C12H10F3N
Molecular Weight	225.21 g/mol
Synonyms	1-[2-(Trifluoromethyl)phenyl]cyclobutanecarbonitrile; α-(2-Trifluoromethylphenyl)cyclobutanecarbonitrile; 2-(Trifluoromethyl)phenyl cyclobutanecarbonitrile; Cyclobutanecarbonitrile, 1-[2-(trifluoromethyl)phenyl]-; 1-(2-Trifluoromethylphenyl)cyclobutanecarbonitrile; 1-(o-Trifluoromethylphenyl)cyclobutanecarbonitrile; 29786-42-3
EINECS	Contact for details

Quality Control

Our 1-(2-(Trifluoromethyl)Phenyl)Cyclobutane-1-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support development projects by offering material suitable for research use and can scale production to meet cGMP or other stringent regulatory requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.