Description

(1R,7Aβ,8S,αs)-Octahydro-6β,8-Dihydroxy-α,3Aβ,5α-Trimethyl-1α,4α,6-Metheno-1H-Indene-1-Acetic Acid is a high-purity, complex polycyclic organic acid derivative of significant interest in advanced pharmaceutical synthesis. Its intricate stereochemistry and functional groups make it a valuable chiral building block and key intermediate for research and development. This compound is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers working on novel therapeutic agents, particularly in steroid-like or complex terpenoid frameworks.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs) with complex polycyclic structures.
• Steroid Analog Research: Used in medicinal chemistry for the development and modification of steroid-like compounds for potential therapeutic applications.
• Asymmetric Synthesis: Acts as a sophisticated chiral starting material or scaffold for constructing molecules with specific three-dimensional configurations.
• Biochemical Research: Employed in academic and industrial laboratories to study enzyme interactions, receptor binding, or metabolic pathways involving complex carboxylic acids.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals, flavors, or fragrances requiring high stereochemical purity.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(1R,7Aβ,8S,αs)-Octahydro-6β,8-Dihydroxy-α,3Aβ,5α-Trimethyl-1α,4α,6-Metheno-1H-Indene-1-Acetic Acid
CAS No.	29598-38-7
Molecular Formula	C16H24O4
Molecular Weight	280.36 g/mol
Synonyms	1H-Indene-1-acetic acid, octahydro-6,8-dihydroxy-α,3a,5-trimethyl-, (1R,3aS,5S,6R,7aR,8S)-rel-; (1R,3aS,5S,6R,7aR,8S)-Octahydro-6,8-dihydroxy-α,3a,5-trimethyl-1,4-methano-1H-indene-1-acetic acid; 6β,8-Dihydroxy-α,3aβ,5α-trimethyl-1α,4α,6-metheno-1H-indene-1-acetic acid; (1R,3aS,5S,6R,7aR,8S)-6,8-Dihydroxy-α,3a,5-trimethyloctahydro-1,4-methanoindene-1-acetic acid; A complex polycyclic dihydroxy carboxylic acid.
EINECS	Contact for details

Quality Control

Our (1R,7Aβ,8S,αs)-Octahydro-6β,8-Dihydroxy-α,3Aβ,5α-Trimethyl-1α,4α,6-Metheno-1H-Indene-1-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and spectroscopic confirmation (NMR, IR, MS) are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.