Description

Triethylammonium Fluoride is a versatile and highly reactive fluoride source and strong organic base, commonly used as a catalyst and reagent in advanced chemical synthesis. Its unique combination of properties makes it invaluable for facilitating challenging fluorination and deprotection reactions under mild conditions. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise control over reaction pathways is critical.

Application

• Nucleophilic Fluorination Reagent: A key reagent for introducing fluorine atoms into organic molecules, crucial for developing pharmaceuticals and agrochemicals with enhanced metabolic stability and bioavailability.
• Catalyst for Silyl Group Deprotection: Widely employed as a highly effective catalyst for the selective removal of silyl protecting groups (e.g., TBDMS, TMS) in complex multi-step organic syntheses, particularly in peptide and nucleotide chemistry.
• Promoter for Condensation and Cyclization Reactions: Acts as a basic catalyst to promote aldol condensations, Knoevenagel reactions, and various heterocycle formations in fine chemical manufacturing.
• Electrolyte Additive: Investigated for use in specialty battery formulations to enhance ionic conductivity and electrode stability.
• Intermediate for Fluorinated Compounds: Serves as a building block or intermediate in the synthesis of more complex fluorinated organic molecules and ionic liquids.
• Research & Development: A fundamental tool in academic and industrial R&D labs for exploring new synthetic methodologies involving fluoride chemistry.

Basic Information

Product Name	Triethylammonium Fluoride
CAS No.	29585-72-6
Molecular Formula	C6H16FN
Molecular Weight	121.20 g/mol
Synonyms	Triethylamine Hydrofluoride; Et3N·HF; Fluorotriethylammonium; Triethylammonium Hydrofluoride; Triethylamine HF Complex; TEA·HF; N,N-Diethylethanaminium Fluoride; Fluoride, triethylammonium
EINECS	Contact for details

Quality Control

Our Triethylammonium Fluoride is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity, consistency, and compliance with relevant industry standards. A comprehensive Certificate of Analysis (COA) detailing assay, identity, and impurity profiles is provided with every shipment to guarantee supply reliability and product integrity for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or solution
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Impurities (HPLC)	≤ 1.0% total
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.