Description

2'-Fluoro-4'-Methylacetophenone is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its value lies in its role as a versatile intermediate for introducing both fluorine and acetylphenyl motifs into complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes.
• Advanced Polymer Chemistry: Incorporated as a monomer or cross-linking agent to create specialty polymers with unique thermal and optical properties.
• Chemical Research & Development: A fundamental reagent for method development in fluorination chemistry and cross-coupling reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrance and flavor ingredients.

Basic Information

Product Name	2'-Fluoro-4'-Methylacetophenone
CAS No.	29427-48-3
Molecular Formula	C9H9FO
Molecular Weight	152.17 g/mol
Synonyms	1-(2-Fluoro-4-methylphenyl)ethanone; 2-Fluoro-4-methylacetophenone; 2'-Fluoro-4'-methylacetophenone; 4'-Methyl-2'-fluoroacetophenone; 2-Fluoro-4-methyl-1-acetylbenzene; 1-Acetyl-2-fluoro-4-methylbenzene; p-Methyl-o-fluoroacetophenone
EINECS	Contact for details

Quality Control

Our 2'-Fluro-4'-Methylacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly closed to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.