Description

Mequitazine CAS NO 29216-28-2 is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) belonging to the phenothiazine class of compounds. It serves as a critical building block in the synthesis of advanced antihistamine medications, offering reliable performance for complex pharmaceutical manufacturing. This compound is essential for research institutions, pharmaceutical development labs, and API producers focused on creating next-generation therapeutic agents.

Application

• Pharmaceutical API Synthesis: Primary use as the active ingredient in the manufacture of antihistamine drugs.
• Clinical Research & Development: Serves as a key reference standard and intermediate in preclinical and clinical studies for allergic conditions.
• Process Chemistry: Used in scaling up and optimizing synthetic routes for commercial drug production.
• Analytical Standard: Employed as a high-purity standard for quality control (QC) and analytical method development (e.g., HPLC, GC).
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for pharmacological studies and molecular research.

Basic Information

Product Name	Mequitazine
CAS No.	29216-28-2
Molecular Formula	C20H22N2S
Molecular Weight	322.47 g/mol
Synonyms	Mequitazine; LM-209; 10-(1-Methyl-3-pyrrolidinylmethyl)phenothiazine; 10-[(1-Methylpyrrolidin-3-yl)methyl]-10H-phenothiazine; 10H-Phenothiazine, 10-[(1-methyl-3-pyrrolidinyl)methyl]-; Metquitazina; Méquitazine; Mequitazinum
EINECS	249-492-6

Quality Control

Our Mequitazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data supporting compliance with pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) is supplied with each batch, documenting key parameters such as assay, purity, and impurity profiles. Our quality commitment ensures the material is suitable for demanding GMP (Good Manufacturing Practice) applications and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.