Description

1-(tert-Butylamino)-3-[[4-(Morpholin-4-Yl)-1,2,5-Thiadiazol-3-Yl]Oxy]Propan-2-Ol CAS NO 29023-48-1 is a specialized organic compound featuring a unique molecular architecture combining morpholine and thiadiazole heterocycles with a propanolamine linker. This structure is of significant interest for its potential as a key synthetic intermediate or active pharmaceutical ingredient (API) in advanced research and development. It is primarily sought by pharmaceutical chemists and agrochemical researchers for the synthesis of novel bioactive molecules targeting specific receptors or enzymes. The compound's defined stereochemistry and functional groups make it a valuable building block for creating libraries of compounds in drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel β-blockers or other cardiovascular agents due to its propanolamine core structure.
• Agrochemical Research: Used in developing new generations of herbicides or fungicides, leveraging the bioactivity of the thiadiazole and morpholine motifs.
• Chemical Biology Probe: Acts as a scaffold for creating tool compounds to study adrenergic or other G-protein coupled receptor (GPCR) pathways.
• Organic Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Material Science Research: Potential use in the synthesis of specialty polymers or ligands for metal complexes, given its multifunctional design.

Basic Information

Product Name	1-(tert-Butylamino)-3-[[4-(Morpholin-4-Yl)-1,2,5-Thiadiazol-3-Yl]Oxy]Propan-2-Ol
CAS No.	29023-48-1
Molecular Formula	C13H24N4O3S
Molecular Weight	316.42 g/mol
Synonyms	Timolol Impurity; 1-(tert-Butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol; 3-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-4-morpholinyl-1,2,5-thiadiazole; (RS)-1-(tert-Butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol; (±)-1-(tert-Butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol; Timolol Related Compound; Propan-2-ol, 1-(1,1-dimethylethyl)amino-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-
EINECS	Contact for details

Quality Control

Our production of 1-(tert-Butylamino)-3-[[4-(Morpholin-4-Yl)-1,2,5-Thiadiazol-3-Yl]Oxy]Propan-2-Ol adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing key parameters such as assay, chiral purity, and impurity profiles are provided to support your regulatory and development needs. We operate under a cGMP-compliant quality management system to ensure traceability and reliability for pharmaceutical-grade inquiries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.