Description

(8S,10S)-8-Ethyl-7,8,9,10-Tetrahydro-1,6,8,10-Tetrahydroxy-5,12-Naphthacenedione is a high-purity, stereochemically defined anthracycline derivative. This compound is valued for its role as a critical pharmaceutical intermediate and a reference standard in advanced research and development. It is primarily required by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical synthesis sectors.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex anthracycline-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used for analytical method development, validation, and quality control (QC/QA) in pharmaceutical manufacturing.
• Biochemical Research: Serves as a precursor or model compound in oncology and molecular biology research.
• Fine Chemical Synthesis: Employed in the development of novel chemical entities and specialty compounds.
• Academic & Industrial R&D: Utilized in studies exploring structure-activity relationships (SAR) of naphthacenedione derivatives.

Basic Information

Product Name	(8S,10S)-8-Ethyl-7,8,9,10-Tetrahydro-1,6,8,10-Tetrahydroxy-5,12-Naphthacenedione
CAS No.	28553-82-4
Molecular Formula	C₂₂H₂₂O₈
Molecular Weight	414.41 g/mol
Synonyms	8-Ethyl-7,8,9,10-tetrahydro-1,6,8,10-tetrahydroxy-5,12-naphthacenedione, (8S,10S)-8-Ethyl-7,8,9,10-tetrahydro-1,6,8,10-tetrahydroxy-5,12-naphthacenedione; 8-Ethyl-7,8,9,10-tetrahydro-1,6,8,10-tetrahydroxy-5,12-naphthacenedione (8S,10S)-; 4-Deoxy-ε-rhodomycinone; 4-Deoxy-ε-rhodomycinone aglycone; ε-Rhodomycinone aglycone, 4-deoxy-; 4-Deoxy-ε-rhodomycinone aglycon
EINECS	Contact for details

Quality Control

Our (8S,10S)-8-Ethyl-7,8,9,10-Tetrahydro-1,6,8,10-Tetrahydroxy-5,12-Naphthacenedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC purity analysis and spectroscopic identification, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a dry, cool, and well-ventilated area.

Specification

Item	Specification
Appearance	Orange to red-brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.