Description

2-(1,1,2,2-Tetrafluoroethoxy)Nitrobenzene is a specialized fluorinated aromatic intermediate of significant interest in advanced organic synthesis. Its unique structure, featuring a tetrafluoroethoxy substituent adjacent to a nitro group, makes it a valuable precursor for constructing complex molecules with tailored electronic and physical properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, particularly those requiring fluorinated motifs for enhanced metabolic stability, bioavailability, or receptor binding affinity.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the introduction of fluorine atoms can improve efficacy and environmental profile.
• Liquid Crystal & Electronic Materials: Serves as a precursor in the synthesis of fluorinated components for liquid crystal displays (LCDs) and organic electronic materials due to its potential influence on dielectric properties and molecular alignment.
• Advanced Polymer Modification: Employed to introduce fluorinated side chains into polymers, aiming to alter surface properties, chemical resistance, or optical characteristics.
• Organic Synthesis Research: A versatile reagent for academic and industrial research exploring novel fluorination reactions, nucleophilic aromatic substitutions, and the development of new catalytic methodologies.

Basic Information

Product Name	2-(1,1,2,2-Tetrafluoroethoxy)Nitrobenzene
CAS No.	28202-31-5
Molecular Formula	C8H5F4NO3
Molecular Weight	239.12 g/mol
Synonyms	1-Nitro-2-(1,1,2,2-tetrafluoroethoxy)benzene; 2-Nitro-1-(1,1,2,2-tetrafluoroethoxy)benzene; Benzene, 1-nitro-2-(1,1,2,2-tetrafluoroethoxy)-; o-(1,1,2,2-Tetrafluoroethoxy)nitrobenzene; 2-(Perfluoroethoxy)nitrobenzene; Nitro(1,1,2,2-tetrafluoroethoxy)benzene
EINECS	Contact for details

Quality Control

Every batch of 2-(1,1,2,2-Tetrafluoroethoxy)Nitrobenzene is produced and tested under a strict quality management system to ensure consistency and reliability for your critical synthesis work. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.