Description

Diacetolol is a key pharmaceutical intermediate and β-adrenergic blocking agent. This compound is crucial for the synthesis of advanced active pharmaceutical ingredients (APIs) targeting cardiovascular conditions. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development and production of β-blocker medications. Our supply ensures high purity and consistent quality for critical R&D and manufacturing processes.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of β-blocker drugs such as acebutolol and its related analogs.
• Active Pharmaceutical Ingredient (API) Research: Serves as a critical building block in medicinal chemistry for developing new cardiovascular therapies.
• Chemical Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of pharmaceutical products.
• Preclinical and Clinical Studies: Employed in pharmacological research to study β-adrenergic receptor antagonism and metabolic pathways.
• Process Chemistry Development: Key starting material for optimizing scalable and cost-effective synthetic routes in pilot plants and commercial manufacturing.

Basic Information

Product Name	Diacetolol
CAS No.	28197-69-5
Molecular Formula	C18H28N2O5
Molecular Weight	352.43 g/mol
Synonyms	N-[3-Acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide; Diacetolol Hydrochloride (salt form); Acebutolol Metabolite; (±)-Diacetolol; 1-(2-Acetyl-4-acetamidophenoxy)-3-(isopropylamino)-2-propanol
EINECS	Contact for details

Quality Control

Our Diacetolol is manufactured and tested under a strict quality management system. We provide material that meets high-purity standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles by validated methods (e.g., HPLC, NMR) is supplied with each batch to ensure traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.