Description

1-(2-Fluorophenyl)Cyclobutanecarbonitrile is a versatile fluorinated organic intermediate of significant interest in advanced chemical synthesis. This compound is valued for its unique structural motif, combining a cyclobutane ring with a fluorinated aromatic system, which is crucial for modulating the physicochemical properties of target molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine atoms is a key strategy for enhancing metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorophenyl group contributes to efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways and creating specialized chemical libraries.
• Fine Chemical Production: Acts as a critical intermediate in the multi-step synthesis of complex fluorinated fine chemicals and specialty polymers.

Basic Information

Product Name	1-(2-Fluorophenyl)Cyclobutanecarbonitrile
CAS No.	28049-63-0
Molecular Formula	C11H10FN
Molecular Weight	175.20 g/mol
Synonyms	2-Fluorophenylcyclobutanecarbonitrile; (2-Fluorophenyl)cyclobutanecarbonitrile; 1-(2-Fluorophenyl)cyclobutanecarbonitrile; Cyclobutanecarbonitrile, 1-(2-fluorophenyl)-; α-(2-Fluorophenyl)cyclobutanecarbonitrile; o-Fluorophenylcyclobutanecarbonitrile; 2-Fluoro-α-(cyclobutylidene)benzenecetonitrile
EINECS	Contact for details

Quality Control

Our production of 1-(2-Fluorophenyl)Cyclobutanecarbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.