Description

Daunomycinol is a key chemical intermediate and aglycone derivative of the anthracycline antibiotic daunorubicin. This compound is of significant interest in pharmaceutical research and development, particularly for the synthesis of novel chemotherapeutic agents and for studying structure-activity relationships. It serves as a critical building block for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors, enabling the development of targeted cancer therapies and advanced drug discovery programs.

Application

• Pharmaceutical Intermediate: Primary use as a key precursor in the synthesis of daunorubicin, doxorubicin, and other anthracycline-based chemotherapeutic agents.
• Biochemical Research: Used as a reference standard and tool compound in oncology research to study DNA intercalation, topoisomerase II inhibition, and mechanisms of action of anthracyclines.
• Medicinal Chemistry: Serves as a core scaffold for the design and development of new anticancer drug candidates with potentially improved efficacy or reduced cardiotoxicity.
• Academic Research: Employed in university and institutional labs for fundamental studies on apoptosis, drug resistance mechanisms, and cancer cell biology.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing organizations (CMOs) for producing specialized, high-value chemical entities.

Basic Information

Product Name	Daunomycinol
CAS No.	28008-55-1
Molecular Formula	C₂₁H₁₈O₈
Molecular Weight	398.36 g/mol
Synonyms	Daunomycinone aglycone; 7,8,9,10-Tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione; (1S,3S)-3-Acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl methyl ketone; Daunorubicinone; 13-Dihydrodaunomycinone; Daunomycin aglycone
EINECS	Contact for details

Quality Control

Our Daunomycinol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and cGMP-grade material requirements where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.