Description

4-Fluorocinnamonitrile is a versatile fluorinated aromatic nitrile building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the fluorine atom and nitrile group enable precise molecular modifications. Industries such as pharmaceutical R&D, agrochemical manufacturing, and specialty chemical production need this high-purity intermediate to create novel compounds with enhanced biological activity and stability.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used to develop novel herbicides and pesticides, where the fluorine atom improves metabolic stability and bioavailability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated components in electronic display and lighting materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and cyano-group transformations to construct complex molecular architectures.
• Fluorine Chemistry Research: A valuable substrate for studying the effects of fluorine substitution on aromatic systems in academic and industrial R&D settings.

Basic Information

Product Name	4-Fluorocinnamonitrile
CAS No.	27530-50-3
Molecular Formula	C9H6FN
Molecular Weight	147.15 g/mol
Synonyms	(E)-3-(4-Fluorophenyl)acrylonitrile; 4-Fluorocinnamomitrile; trans-4-Fluorocinnamonitrile; (E)-3-(4-Fluorophenyl)-2-propenenitrile; p-Fluorocinnamonitrile; 4-Fluorobenzylideneacetonitrile; β-(4-Fluorophenyl)acrylonitrile; (E)-4-Fluorocinnamomitrile
EINECS	Contact for details

Quality Control

Our 4-Fluorocinnamonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and purity while monitoring for specified impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.